PROGRAMS | 1.15.2025

Grafton Sciences launches program to solve all disease

Today we are launching a program whose goal is to solve all disease — by developing a unified scientific framework that connects early detection, therapeutic design, and biological modeling within one coordinated system of discovery.

The effort reflects a simple observation: progress in medicine has been constrained by disciplinary separation. Biology, chemistry, materials science, and computation have each advanced rapidly, but largely in isolation. We believe that by co-developing these domains together — by designing molecules, devices, and models in a single closed loop — it is possible to generate solutions that no single field could achieve independently.

Our focus is on building a complete stack of discovery, spanning early detection, intervention, and simulation. This approach aims not only to treat disease but to anticipate it — detecting cellular dysregulation before pathology emerges, designing molecular responses that restore equilibrium, and continuously refining models of human biology as new data flow through the system.

This program is one of several initiatives we are undertaking on the path towards building physical superintelligence — systems capable of autonomously exploring and engineering the physical world. Disease is, at its core, a problem of organization: a breakdown of coherence across molecular and cellular processes. Understanding and repairing those breakdowns at scale requires systems that can learn across physics, chemistry, and biology simultaneously.